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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
16.36
Human Site:
S2223
Identified Species:
36
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2223
P
Q
Q
S
Q
H
A
S
P
Q
R
Y
I
S
E
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
R2672
L
P
A
F
S
P
G
R
L
S
R
G
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2220
P
R
Q
G
Q
H
A
S
P
Q
R
Y
I
S
E
Dog
Lupus familis
XP_547425
2465
277756
S2375
G
Q
Q
S
Q
H
C
S
P
Q
R
Y
I
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S2183
P
Q
Q
G
Q
H
P
S
P
Q
H
Y
I
S
E
Rat
Rattus norvegicus
Q07652
2222
252098
S2132
P
Q
Q
G
Q
H
P
S
P
Q
H
Y
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
K2105
E
G
L
G
R
Y
A
K
D
P
K
F
V
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
T1747
L
I
A
R
K
M
N
T
L
Y
G
S
N
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
D1769
R
D
R
D
R
D
R
D
R
L
H
E
Y
D
L
Honey Bee
Apis mellifera
NP_001159376
1904
215872
L1822
A
N
I
N
F
P
K
L
N
A
S
P
T
H
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1884
V
R
L
Q
M
D
E
R
P
P
H
Y
D
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
20
86.6
86.6
N.A.
80
80
N.A.
N.A.
13.3
N.A.
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
80
80
N.A.
N.A.
46.6
N.A.
20
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
0
28
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
19
0
10
10
0
0
0
10
10
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
64
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
0
37
0
0
10
0
0
0
10
10
0
0
10
% G
% His:
0
0
0
0
0
46
0
0
0
0
37
0
0
10
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
46
0
0
% I
% Lys:
0
0
0
0
10
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
19
0
19
0
0
0
0
10
19
10
0
0
10
0
10
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
10
0
10
0
0
0
10
0
0
% N
% Pro:
37
10
0
0
0
19
19
0
55
19
0
10
0
10
0
% P
% Gln:
0
37
46
10
46
0
0
0
0
46
0
0
0
0
0
% Q
% Arg:
10
19
10
10
19
0
10
19
10
0
37
0
0
0
0
% R
% Ser:
0
0
0
19
10
0
0
46
0
10
10
10
0
64
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
55
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _